Reaching 100% in The Lost and Damned means finishing Johnny Klebitz's story and a set list of side content:
- Story missions: 65% (22 missions at 2.73% each, plus a 5% bonus for "Hit the Pipe").
- Side jobs: 10% (Angus' 10 bike thefts and Stubbs' 5 Dirty Laundry jobs, 5% each).
- Friend activities: 5% (7 activities with Terry or Clay).
- Random characters: 5% (Malc and Dave Grossman).
- Activities: 5% (win arm wrestling, air hockey, pool and darts).
- Side objectives: 10% (all 12 bike races, 50 seagulls and 25 gang wars, 3.33% each).
Bowling, QUB3D, Hi-Lo and hanging out at the clubhouse do not count. No achievement is tied to 100%.